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Intrapleural mitoxantrone for the palliative treatment of malignant pleural effusions.

Abstract
A group of 21 patients with malignant pleural effusions were treated with the instillation of 40 mg mitoxantrone intrapleurally, after complete fluid drainage. There was a 100% complete response rate with no toxic effects (0%). The mean survival of the patients was 57.1 weeks.
AuthorsM Morales, M C Expósito
JournalSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (Support Care Cancer) Vol. 3 Issue 2 Pg. 147-9 (Mar 1995) ISSN: 0941-4355 [Print] Germany
PMID7539702 (Publication Type: Clinical Trial, Journal Article)
Chemical References
  • Mitoxantrone
Topics
  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Instillation, Drug
  • Male
  • Middle Aged
  • Mitoxantrone (administration & dosage)
  • Palliative Care
  • Pleural Effusion, Malignant (drug therapy)
  • Treatment Outcome

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