[A case of prostatic adenocarcinoma with pulmonary metastases--diagnosis by transbronchial lung biopsy and immunohistochemistry].

Abstract

Metastatic pulmonary adenocarcinoma was found in a 79-year-old man, who had symptoms of general malaise and poor appetite. An extensive work-up including a transurethral resection of the prostate, failed to establish the primary site of the malignancy. By administering chlormadinone acetate for prostatic hypertrophy, the pulmonary metastases improved dramatically. The tumor cells in the lung, which had previously been obtained by transbronchial lung biopsy, stained positive for prostatic acid phosphatase and prostatic specific antigen. These data suggested that prostatic carcinoma had metastasized to the lung. The prostatic carcinoma was finally confirmed at autopsy.

• Authors: K Nishi, T Amemiya, T Ooka, H Kurumaya, M Fujimaru, T Matsuda
• Journal: Nihon Kyobu Shikkan Gakkai zasshi (Nihon Kyobu Shikkan Gakkai Zasshi) Vol. 32 Issue 10 Pg. 1001-5 (Oct 1994) ISSN: 0301-1542 [Print] Japan
• PMID: 7531254 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Biomarkers, Tumor
• Acid Phosphatase
• Prostate-Specific Antigen

Topics

• Acid Phosphatase (analysis)
• Adenocarcinoma (secondary)
• Aged
• Biomarkers, Tumor (analysis)
• Humans
• Immunohistochemistry
• Lung (metabolism, pathology)
• Lung Neoplasms (secondary)
• Male
• Prostate-Specific Antigen (analysis)
• Prostatic Neoplasms (pathology)