Rapid staining with carcinoembryonic antigen aids limited excision of extramammary Paget's disease treated by Mohs surgery.

Abstract

Extensive extramammary Paget's (EMPD) disease of the perineum in a 68-year-old man was treated by Mohs surgery. To facilitate identification of involved tissue a rapid staining carcinoembryonic antigen was used. This technique proved a useful adjunct to conventional hemotoxylin-eosin (H&E) stains. It was especially useful in highlighting involvement in areas of marked dysplasia/artifact where discrimination is often difficult. It is recommended that such a technique offers considerable benefits over H&E staining when confronted by such tissue morphology.

• Authors: D W Harris, D A Kist, K Bloom, C B Zachary
• Journal: The Journal of dermatologic surgery and oncology (J Dermatol Surg Oncol) Vol. 20 Issue 4 Pg. 260-4 (Apr 1994) ISSN: 0148-0812 [Print] United States
• PMID: 7513002 (Publication Type: Case Reports, Journal Article)

Chemical References

• Carcinoembryonic Antigen

Topics

• Aged
• Carcinoembryonic Antigen (analysis)
• Genital Neoplasms, Male (pathology, surgery)
• Humans
• Male
• Mohs Surgery
• Paget Disease, Extramammary (pathology, surgery)
• Scrotum
• Skin Transplantation
• Staining and Labeling (methods)