[A case of stage IIIB2 infantile yolk sac tumor of testis achieved complete remission by "COMPE" chemotherapy].

Abstract

A case of metastatic infantile yolk sac tumor of testis is reported herein. The patient was 23 months old with a painless swelling of the right scrotal contents. Histological examination revealed yolk sac tumor. Six months later, the serum alpha-fetoprotein (AFP) was re-elevated and solitary lung metastasis had developed. After 4 courses of chemotherapy with cisplatin (CDDP), vincristine (VCR), methotrexate (MTX), peplomycin (PEP) and Etoposide (COMPE), serum AFP was normalized and lung metastasis disappeared. He has shown no evidence of disease for 5 years with normal physical growth. Aggressive chemotherapy including CDDP might be used for Stage III infantile testicular cancer.

• Authors: T Ueda, T Yamauchi, M Kokuho, K Ishibashi, S Kawakami, J Yonese, T Kawai
• Journal: Hinyokika kiyo. Acta urologica Japonica (Hinyokika Kiyo) Vol. 39 Issue 12 Pg. 1183-6 (Dec 1993) ISSN: 0018-1994 [Print] Japan
• PMID: 7506867 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Bleomycin
• Peplomycin
• Vincristine
• Etoposide
• Cisplatin
• Methotrexate

Topics

• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Bleomycin (administration & dosage)
• Cisplatin (administration & dosage)
• Endodermal Sinus Tumor (drug therapy, secondary)
• Etoposide (administration & dosage)
• Humans
• Infant
• Lung Neoplasms (drug therapy, secondary)
• Male
• Methotrexate (administration & dosage)
• Peplomycin
• Remission Induction
• Testicular Neoplasms (drug therapy, pathology)
• Vincristine (administration & dosage)