Abstract |
We found a significant increase in fibronectin receptor (FNR) levels in the sera of adult human immunodeficiency virus type 1 (HIV-1)-infected patients, especially in those with AIDS (1,026.9 +/- 583.9 ng/ml; P < 0.0001). In contrast, AIDS patients with neurologic disorders and HIV-1-seropositive patients showed normal levels of FNR in serum. In addition, HIV-1-infected children showed increased levels of FNR in serum (824.4 +/- 333.5 ng/ml; P = 0.03). We suggest that an increase of FNR levels in AIDS patients is related to enhanced expression of FNR on HIV-1-infected cells.
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Authors | D Torre, C Zeroli, A Pugliese, M Giola, G Ferrario, G Bonetta, M Issi, R Martegani, F Speranza, G P Fiori |
Journal | Clinical and diagnostic laboratory immunology
(Clin Diagn Lab Immunol)
Vol. 1
Issue 3
Pg. 348-50
(May 1994)
ISSN: 1071-412X [Print] United States |
PMID | 7496974
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Acquired Immunodeficiency Syndrome
(immunology)
- Adolescent
- Adult
- Child
- Child, Preschool
- Female
- HIV Infections
(blood, immunology)
- HIV-1
(immunology)
- Humans
- Infant
- Male
- Middle Aged
- Receptors, Fibronectin
(analysis, physiology)
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