Effects of vitamin E on endothelial function in men after myocardial infarction.

Abstract

This study showed that endothelial dysfunction is present in men 3 to 6 months after myocardial infarction, but was unable to show any improvement in endothelial function after 3 months of therapy with vitamin E 800 IU/day. Further studies are necessary to determine whether higher doses or a longer course of vitamin E, or whether other antioxidant agents with or without lipid-modifying activity, would improve endothelial function.

• Authors: T G Elliott, J D Barth, G B Mancini
• Journal: The American journal of cardiology (Am J Cardiol) Vol. 76 Issue 16 Pg. 1188-90 (Dec 01 1995) ISSN: 0002-9149 [Print] United States
• PMID: 7484909 (Publication Type: Journal Article)

Chemical References

• Antioxidants
• Vitamin E
• Nitroprusside
• Acetylcholine

Topics

• Acetylcholine (pharmacology)
• Antioxidants (pharmacology)
• Blood Flow Velocity (drug effects)
• Dose-Response Relationship, Drug
• Endothelium, Vascular (drug effects, physiopathology)
• Forearm (blood supply)
• Humans
• Male
• Middle Aged
• Myocardial Infarction (physiopathology)
• Nitroprusside (pharmacology)
• Time Factors
• Vitamin E (pharmacology)