Urodynamic effects of Prolase 2 laser prostatectomy in benign prostatic hyperplasia.

Abstract

This prospective study was undertaken to evaluate the safety and efficacy of visual laser ablation of the prostate with the Prolase 2 sidefiring neodymium: YAG laser fiber in patients with symptomatic bladder outlet obstruction due to benign prostatic hyperplasia (BPH). The Prolase 2 fiber is a non-contact sidefiring fiber, producing coagulation of the prostatic tissue. Our study describes the results obtained in 30 patients who underwent VLAP with a mean follow-up of 6 months. The evaluation of symptoms according to the WHO International Prostate Symptom Score and Quality of Life Score (IPSS and QL) demonstrated a significant subjective response rate (p < 0.001). Objective assessment of treatment with peak and average urinary flow rates, post-void residual urine volumes and pressure-flow urodynamic studies showed a significant improvement after treatment (p < 0.001). Ultrasonic assessment of prostatic volumes at 6 months showed a mean decrease in total volume of 37% after laser prostatectomy. The early and late complications of the treatment are presented but overall toxicity is low. Laser prostatectomy performed with the Prolase 2 fiber seems to be safe and efficacious for BPH patients but long term efficacy and retreatment rates have to be awaited.

• Authors: P Van Erps, S Schapmans, J Cortvriend, C D'Hont, L J Denis
• Journal: Acta urologica Belgica (Acta Urol Belg) Vol. 63 Issue 3 Pg. 39-43 (Sep 1995) ISSN: 0001-7183 [Print] Belgium
• PMID: 7484521 (Publication Type: Clinical Trial, Journal Article)

Topics

• Aged
• Humans
• Laser Therapy (methods)
• Male
• Middle Aged
• Postoperative Complications (etiology)
• Prospective Studies
• Prostatic Hyperplasia (physiopathology, surgery)
• Quality of Life
• Treatment Outcome
• Urodynamics