HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Porcine heterograft valve replacement in carcinoid heart disease.

Abstract
A 53-year-old man with a pancreatic carcinoid tumor and liver metastases had the carcinoid syndrome with involvement of the tricuspid valve by carcinoid plaque. The mitral valve was involved by unrelated myxomatous degeneration (floppy valve). Each valve was replaced by a Hancock glutaraldehyde-prepared porcine heterograft prosthesis. When the patient died of complications of the tumor 8 months postoperatively, both valves had clinically normal function. Nevertheless, the carcinoid plaque, which was present in all four cardiac chambers and almost completely covered the endocardial surfaces of both atria, extended onto both prostheses. This eventually might have interfered with prosthetic valve function.
AuthorsF J Schoen, R J Hausner, J F Howell, H L Beazley, J L Titus
JournalThe Journal of thoracic and cardiovascular surgery (J Thorac Cardiovasc Surg) Vol. 81 Issue 1 Pg. 100-5 (Jan 1981) ISSN: 0022-5223 [Print] United States
PMID7453210 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
Topics
  • Bioprosthesis
  • Carcinoid Tumor (secondary, surgery)
  • Heart Neoplasms (secondary, surgery)
  • Heart Valve Diseases (complications)
  • Heart Valve Prosthesis
  • Humans
  • Male
  • Malignant Carcinoid Syndrome (complications)
  • Middle Aged
  • Myocardium (pathology)
  • Pancreatic Neoplasms (complications)
  • Tricuspid Valve (pathology, surgery)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: