Nephrotic syndrome with slight proliferative changes in the glomeruli: response to prednisone.

Abstract

Seven patients with slight but definite proliferative changes in the glomeruli achieved complete remission of the nephrotic syndrome when treated with prednisone. The patterns of response and, in three cases, repeated relapse and response suggested that this was more than a coincidental spontaneous cure. A controlled trial of corticosteroids in patients with slight proliferative glomerulonephritis and severe nephrotic syndrome should be carried out to verify these results.

• Authors: H Rashid, S Ezedum, A R Morley, D N Kerr
• Journal: British medical journal (Br Med J) Vol. 281 Issue 6236 Pg. 347-50 (Aug 02 1980) ISSN: 0007-1447 [Print] England
• PMID: 7427273 (Publication Type: Journal Article)

Chemical References

• Prednisone

Topics

• Adolescent
• Adult
• Female
• Glomerulonephritis (drug therapy)
• Humans
• Kidney Glomerulus (ultrastructure)
• Male
• Microscopy, Electron
• Nephrotic Syndrome (drug therapy, pathology)
• Prednisone (therapeutic use)
• Proteinuria (drug therapy)