[Antibiotic prophylaxis in colon surgery with Cefazolin].

Abstract

In a prospective randomized and controlled double-blind trial the effect of prophylactic systemic administration of Cefazolin in elective colorectal surgery on postoperative wound infection was investigated. The incidence of wound infection was significantly reduced (P less than 0.01) from 32% in the control group to 10% in the treated group. Furthermore there was a significant reduction (P less than 0.05) in hospital stay of about 3 days.

• Authors: M Dürig, U Neff, W W Rittmann, A Leutenegger, M Oberholzer, G Wolff
• Journal: Helvetica chirurgica acta (Helv Chir Acta) Vol. 46 Issue 5-6 Pg. 721-6 (Feb 1980) ISSN: 0018-0181 [Print] Switzerland
• Vernacular Title: Antibiotikaprophylaxe in der Kolonchirurgie mit Cefazolin.
• PMID: 7399948 (Publication Type: Clinical Trial, English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Cefazolin

Topics

• Cefazolin (therapeutic use)
• Colon (surgery)
• Humans
• Length of Stay
• Surgical Wound Infection (prevention & control)