Successful treatment of a patient with retractile mesenteritis with prednisone and azathioprine.

Abstract

A patient with retractile mesenteritis is discussed, who presented with a huge 15 X 15-cm inflammatory mass involving the root of the mesentery. Gradually the patient developed duodenal obstruction for which it was necessary to perform a gastroileostomy. Because of a relentless downhill course with fever, weight loss, general malaise, and fatigue, it was finally decided to treat the patient with prednisone and azathioprine. Upon institution of this treatment there was a steady, progressive clinical amelioration with disappearance of fever, improvement in laboratory findings, and gradual regression of the lesion until it became a well-delineated hard mass that was thought to be the end stage of fibrosis. Early trial with such a treatment, once the diagnosis is firmly established, should be considered.

• Authors: G N Tytgat, K Roozendaal, W Winter, M R Esseveld
• Journal: Gastroenterology (Gastroenterology) Vol. 79 Issue 2 Pg. 352-6 (Aug 1980) ISSN: 0016-5085 [Print] United States
• PMID: 7399242 (Publication Type: Case Reports, Journal Article)

Chemical References

• Azathioprine
• Prednisone

Topics

• Azathioprine (administration & dosage)
• Drug Therapy, Combination
• Female
• Humans
• Inflammation (diagnosis, drug therapy)
• Mesentery
• Middle Aged
• Prednisone (administration & dosage)