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Beneficial effect of cholestyramine in sclerosing cholangitis.

Abstract
Cholestyramine exerted a beneficial effect on the course of a patient with sclerosing cholangitis associated with ulcerative proctitis. Over a 6.5-yr period, discontinuation of cholestyramine resulted in episodes of RUQ pain and/or appearance of abnormalities in liver tests. Readministration of the resin was followed by disappearance of symptoms and normalization of test resuls. The mechanism of the beneficial effect of cholestyramine was not elucidated.
AuthorsD E Polter, V Gruhl, E H Eigenbrodt, B Combes
JournalGastroenterology (Gastroenterology) Vol. 79 Issue 2 Pg. 326-33 (Aug 1980) ISSN: 0016-5085 [Print] United States
PMID7399237 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Cholestyramine Resin
Topics
  • Adolescent
  • Adult
  • Cholangitis (complications, diagnosis, drug therapy)
  • Cholestyramine Resin (therapeutic use)
  • Humans
  • Male
  • Middle Aged
  • Proctitis (complications)
  • Sclerosis

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