HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Thrombosis in patients with the lupus anticoagulant.

Abstract
A retrospective study was carried out to determine the frequency of thrombosis in patients with the lupus anticoagulant. Thirty-five patients fulfilled laboratory criteria for the diagnosis of the lupus anticoagulant. Eight of these patients had evidence of clinically significant thrombosis while their plasma showed a prolonged partial thromboplastin time due to the anticoagulant. Four of the patients wity thrombosis had concurrent autoimmune disease and three other patients were receiving phenothiazine medication. Moderate thrombocytopenia was noted in four patients with thrombosis. None of the patients with the lupus anticoagulant bled abnormally. This study suggests that patients with the lupus anticoagulant may be at increased risk of thrombosis.
AuthorsJ R Mueh, K D Herbst, S I Rapaport
JournalAnnals of internal medicine (Ann Intern Med) Vol. 92 Issue 2 Pt 1 Pg. 156-9 (Feb 1980) ISSN: 0003-4819 [Print] United States
PMID7352719 (Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, P.H.S.)
Topics
  • Adolescent
  • Adult
  • Aged
  • Blood Coagulation
  • Female
  • Humans
  • Lupus Erythematosus, Systemic (blood)
  • Male
  • Pulmonary Embolism (blood)
  • Retrospective Studies
  • Thrombophlebitis (blood)
  • Thrombosis (blood)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: