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[Surgical treatment of pituitary adenomas. An analysis of 188 cases (author's transl)].

Abstract
The authors report on a series of 188 patients operated upon for pituitary tumour. Since 12 operations were performed because of local recurrence, the total number of operations was 200 : 27 by the intracranial route and 173 by the naso-sphenoidal route. Four deaths (17%) followed surgery by the former route and three (1.8%) by the latter route. During the decade under review surgical indications have decreased for large tumours belatedly diagnosed and increased for micro-adenomas giving rise to endocrine symptoms only, notably prolactin-secreting adenomas. Improved knowledge of histopathology has resulted in the classification being altered : the conventional division into eosinophilic and chromophobe adenomas has been abandoned to be replaced by cellular types corresponding to the various hormone-producing and functional adenomas. Also a new type has appeared : oncocytoma. Secreting adenomas generally have a better prognosis than non-secreting adenomas, would it be only because they are smaller. Technical advances in operations almost exclusively performed nowadays by the naso-sphenoidal route have improved the results with regard to sight. Sight is now improved in 70.5% of the cases and completely restored in 32.4%.
AuthorsJ P Haguenauer, A Goutelle
JournalAnnales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris (Ann Otolaryngol Chir Cervicofac) Vol. 98 Issue 4-5 Pg. 207-12 ( 1981) ISSN: 0003-438X [Print] France
Vernacular TitleLa chirurgie des tumeurs hypophysaires, Analyse de 188 observations.
PMID7325515 (Publication Type: Journal Article)
Chemical References
  • Prolactin
  • Growth Hormone
Topics
  • Adenoma (metabolism, surgery)
  • Adenoma, Chromophobe (surgery)
  • Adolescent
  • Adult
  • Female
  • Growth Hormone (metabolism)
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Pituitary Neoplasms (metabolism, surgery)
  • Prolactin (metabolism)
  • Visual Fields

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