Abstract |
The authors report on a series of 188 patients operated upon for pituitary tumour. Since 12 operations were performed because of local recurrence, the total number of operations was 200 : 27 by the intracranial route and 173 by the naso-sphenoidal route. Four deaths (17%) followed surgery by the former route and three (1.8%) by the latter route. During the decade under review surgical indications have decreased for large tumours belatedly diagnosed and increased for micro- adenomas giving rise to endocrine symptoms only, notably prolactin-secreting adenomas. Improved knowledge of histopathology has resulted in the classification being altered : the conventional division into eosinophilic and chromophobe adenomas has been abandoned to be replaced by cellular types corresponding to the various hormone-producing and functional adenomas. Also a new type has appeared : oncocytoma. Secreting adenomas generally have a better prognosis than non-secreting adenomas, would it be only because they are smaller. Technical advances in operations almost exclusively performed nowadays by the naso-sphenoidal route have improved the results with regard to sight. Sight is now improved in 70.5% of the cases and completely restored in 32.4%.
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Authors | J P Haguenauer, A Goutelle |
Journal | Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris
(Ann Otolaryngol Chir Cervicofac)
Vol. 98
Issue 4-5
Pg. 207-12
( 1981)
ISSN: 0003-438X [Print] France |
Vernacular Title | La chirurgie des tumeurs hypophysaires, Analyse de 188 observations. |
PMID | 7325515
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adenoma
(metabolism, surgery)
- Adenoma, Chromophobe
(surgery)
- Adolescent
- Adult
- Female
- Growth Hormone
(metabolism)
- Humans
- Male
- Middle Aged
- Neoplasm Recurrence, Local
- Pituitary Neoplasms
(metabolism, surgery)
- Prolactin
(metabolism)
- Visual Fields
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