Abstract |
At a dosage level of 8 to 10 mg/kg body-weight daily for 120 days nifurtimox was associated with clinical healing of cutaneous leishmaniasis in five of eight patients. At a dosage level of 20 mg/kg body-weight daily for 10 days in six of 10 patients the skin ulcer healed. Results and the reasons why both schemes are impracticable are briefly discussed.
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Authors | M F Guerra, P D Marsden, C C Cuba, A C Barretto |
Journal | Transactions of the Royal Society of Tropical Medicine and Hygiene
(Trans R Soc Trop Med Hyg)
Vol. 75
Issue 3
Pg. 335-7
( 1981)
ISSN: 0035-9203 [Print] England |
PMID | 7324099
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Aged
- Child
- Drug Administration Schedule
- Female
- Humans
- Leishmaniasis
(drug therapy)
- Leishmaniasis, Mucocutaneous
(drug therapy)
- Male
- Middle Aged
- Nifurtimox
(administration & dosage, adverse effects, therapeutic use)
- Nitrofurans
(therapeutic use)
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