Nerve growth from nodes of Ranvier in inactive muscle.

Abstract	Paralysis of mouse gluteus maximus muscles with botulinum toxin not only evoked the expected sprouting from nerve terminals but also induced growth from some nodes of Ranvier close to the endplate region. This finding shows that nerve degeneration is not essential for nodal sprouting and supports the hypothesis that inactive muscle liberates a motor nerve growth factor.
Authors	W G Hopkins, M C Brown, R J Keynes
Journal	Brain research (Brain Res) Vol. 222 Issue 1 Pg. 125-8 (Oct 05 1981) ISSN: 0006-8993 [Print] Netherlands
PMID	7296258 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References	Botulinum Toxins
Topics	Animals Axons (physiology) Botulinum Toxins (pharmacology) Female Mice Motor Neurons (physiology) Muscle Denervation Nerve Degeneration Nerve Regeneration Ranvier's Nodes (drug effects, physiology)

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