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Autorosette formation of erythrocytes on peripheral blood mononuclear cells in dogs vaccinated with canine distemper live-virus vaccine.

Abstract
A time course study of the peripheral blood leukocytes of dogs vaccinated with canine distemper live virus (a paramyxovirus) vaccines showed that autorosette-forming leukocytes appeared from day 3 to day 10 after vaccination. The number of these cells peaked at day 7 when as many as 35% of mononuclear cells formed rosettes with autologous erythrocytes. In contrast, in nonvaccinated dogs, only 0.6 +/- 0.3% (standard error of the mean) of mononuclear cells formed rosettes throughout the 2-week period.
AuthorsJ P Chandler, T J Yang
JournalInfection and immunity (Infect Immun) Vol. 33 Issue 2 Pg. 482-4 (Aug 1981) ISSN: 0019-9567 [Print] United States
PMID7275313 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Vaccines, Attenuated
  • Viral Vaccines
Topics
  • Animals
  • Distemper Virus, Canine (immunology)
  • Kinetics
  • Leukocyte Count
  • Leukocytes (immunology)
  • Rosette Formation
  • Vaccination
  • Vaccines, Attenuated (pharmacology)
  • Viral Vaccines (pharmacology)

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