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Experience with cellulose acetate-coated activated charcoal haemoperfusion in the treatment of severe hypnotic drug intoxication.

Abstract
A haemoperfusion column containing activated charcoal coated with cellulose acetate was used to treat 7 patients with barbiturate or ethchlorvynol poisoning. Six of the patients showed marked lightening of coma and all showed a significant fall in plasma drug concentration. Plasma drug clearance and platelet loss were similar to those reported for other coated charcoal columns. Cellulose acetate-coated charcoal haemoperfusion may reduce the period of coma in severe poisoning with barbiturates and other hypnotic drugs and thus the morbidity and mortality.
AuthorsP Crome, G Hampel, B Widdop, R Goulding
JournalPostgraduate medical journal (Postgrad Med J) Vol. 56 Issue 661 Pg. 763-6 (Nov 1980) ISSN: 0032-5473 [Print] England
PMID7267478 (Publication Type: Journal Article)
Chemical References
  • Barbiturates
  • Charcoal
  • acetylcellulose
  • Ethchlorvynol
  • Cellulose
Topics
  • Adult
  • Barbiturates (poisoning)
  • Cellulose (analogs & derivatives)
  • Charcoal
  • Ethchlorvynol (poisoning)
  • Female
  • Hemoperfusion
  • Humans
  • Male
  • Middle Aged

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