[Endocrine effect of L-DOPA in treating the amenorrhea-galactorrhea syndrome].

Abstract

L-DOPA effect on the level of dopamine, hypophyseal luteinizing hormone and total estrogen excretion was studied in the treatment of patients with the amenorrhea-galactorrhea syndrome. The data obtained show positive L-DOPA effect on hypothalamic-hypophyseal-ovarian relationships in the majority of patients that makes it useful in therapeutic practice. The short-term course of L-DOPA administration combined with systematic studies of dopamine and hypophyseal luteinizing hormone excretion may be recommended as a functional test for differential diagnosis of central menstrual dysfunction.

• Authors: G P Koreneva, F V Shikaeva
• Journal: Problemy endokrinologii (Probl Endokrinol (Mosk)) Vol. 26 Issue 6 Pg. 25-8 ( 1980) ISSN: 0375-9660 [Print] Russia (Federation)
• Vernacular Title: Endokrinnyĭ éffekt L-DOFA pri lechenii bol'nykh s sindromom amenorei-galaktorei.
• PMID: 7192862 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Estrogens
• Levodopa
• Luteinizing Hormone
• Dopamine

Topics

• Adult
• Amenorrhea (drug therapy)
• Chronic Disease
• Dopamine (urine)
• Estrogens (urine)
• Female
• Galactorrhea (drug therapy)
• Humans
• Hypothalamo-Hypophyseal System (drug effects)
• Lactation Disorders (drug therapy)
• Levodopa (therapeutic use)
• Luteinizing Hormone (urine)
• Ovary (drug effects)
• Pregnancy
• Syndrome
• Time Factors