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Seizures and transient cortical blindness associated with cis-platinum (II) diamminedichloride (PDD) therapy in a thirty-year-old man.

Abstract
Cis-Platinum is a phase II chemotherapeutic agent effective against a variety of tumors. Known toxic effects include gastrointestinal, renal, audiologic, and hematologic as well as idiosyncratic and atopic. A 30-year-old male who was treated with cis-Platinum diamminedichloride II for disseminated embryonal cell carcinoma of the testicle developed seizures and cortical blindness.
AuthorsI J Berman, M P Mann
JournalCancer (Cancer) Vol. 45 Issue 4 Pg. 764-6 (Feb 15 1980) ISSN: 0008-543X [Print] United States
PMID7188878 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Platinum
  • Cisplatin
Topics
  • Adult
  • Blindness (chemically induced)
  • Cisplatin (adverse effects)
  • Humans
  • Male
  • Platinum (blood, cerebrospinal fluid)
  • Seizures (chemically induced)
  • Teratoma (drug therapy, metabolism)
  • Testicular Neoplasms (drug therapy, metabolism)
  • Time Factors

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