[Significance of the study of leucine aminopeptidase activity of the blood serum in patients with suppurative surgical infections].

Abstract

A study of the diagnostic and prognostic significance of determining the leucineaminopeptidase activity in the blood serum was carried out in patients suffering from suppurative surgical infections. The obtained results reveal the important role of leucineaminopeptidase (LAP) in the pathogenesis of developing septic complications in these patients. A local suppurative process does not cause considerable changes of LAP activity of the blood serum. The generalization of infection however is accompanied by a marked hyperfermentemia. A persistent and manifest increase of LAP during several days (higher than ten times and more) is a poor prognostic sign.

• Authors: L L Schimkevitsch, B M Kostjutschönok, W G Istratov, A M Swetuchin
• Journal: Zentralblatt fur Chirurgie (Zentralbl Chir) Vol. 107 Issue 18 Pg. 1169-75 ( 1982) ISSN: 0044-409X [Print] Germany
• Vernacular Title: Die Bedeutung der Untersuchung der Aktivität von Leuzynaminopeptidase des Blutserums bei Kranken mit eitrigen chirurgischen Infektionen.
• PMID: 7180233 (Publication Type: English Abstract, Journal Article)

Chemical References

• Leucyl Aminopeptidase

Topics

• Fever (enzymology)
• Humans
• Kinetics
• Leucyl Aminopeptidase (blood)
• Male
• Prognosis
• Sepsis (enzymology)
• Surgical Wound Infection (enzymology)