Abstract |
The authors have treated: a) 48 cases of E. histolytica histolytica intestinal amoebiasis by a single dose of 35 mg/kg of secnidazole with 98 p. 100 of parasitological success; b) 122 cases of E. histolytica minuta with several procedures: a unique dose of 25 mg/kg gives no success in 16.6 p. 100 of the cases, but the same single dose during three days gets only 2 p. 100 of failure; c) 22 cases of hepatic amoebiasis by a daily dose of 25 to 33 mg/kg during 5 days with success in every cases. Tolerance has been excellent. These short cures, facilitated by the long half-life of secnidazole are particularly easy to apply in developing countries.
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Authors | J Cesari, M Condat, Y Gendron, P Saint-Andre, J Thomas, G Charmot |
Journal | Medecine tropicale : revue du Corps de sante colonial
(Med Trop (Mars))
1982 Sep-Oct
Vol. 42
Issue 5
Pg. 527-30
ISSN: 0025-682X [Print] France |
Vernacular Title | Le traitement de l'amibiase par le secnidazole en cure courte. |
PMID | 7154901
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Metronidazole
- secnidazole
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Topics |
- Adult
- Amebiasis
(drug therapy)
- Child
- Drug Administration Schedule
- Dysentery, Amebic
(drug therapy)
- Entamoebiasis
(drug therapy)
- Female
- Humans
- Liver Abscess, Amebic
(drug therapy)
- Male
- Metronidazole
(administration & dosage, adverse effects, analogs & derivatives)
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