[Peculiar secretory activity of endometrial cancer cells during progestational therapy].

Abstract

Effect of progestagen-norsteroids on the cells of endometrial carcinoma was studied. It was established that as an effect of treatment with large doses of progestagen (100 mg/day) in about 4--6 weeks carcinoma cells show a peculiar increased secretory activity. It seems likely, that this secretory activity proceeds on the account of the growth-potencial of tumour cells. Thus, as a result the growth of the tumour ceases, or in optimal cases stops.

• Authors: Z Szarvas
• Journal: Morphologiai es igazsagugyi orvosi szemle (Morphol Igazsagugyi Orv Sz) Vol. 18 Issue 2 Pg. 101-6 (Apr 1978) ISSN: 0540-889X [Print] Hungary
• Vernacular Title: Sajátos szekréciós tevékenység az endometrium carcinoma sejtjeiben progesztatív kezelés kapcsán.
• PMID: 714043 (Publication Type: Journal Article)

Chemical References

• Norethindrone

Topics

• Adenocarcinoma (metabolism, ultrastructure)
• Endometrium (drug effects, metabolism, ultrastructure)
• Female
• Humans
• Norethindrone (pharmacology, therapeutic use)
• Secretory Rate (drug effects)
• Uterine Neoplasms (metabolism, ultrastructure)