Intraoperative use of nifedipine for hemodynamic collapse due to coronary artery spasm following myocardial revascularization.

Abstract

Sudden hemodynamic collapse in the perioperative period following myocardial revascularization may be due to coronary artery spasm. Nitroglycerin has been the standard treatment for this; however, it is not always effective, and the resultant morbidity and mortality are high. We present the case of a patient in whom sudden hemodynamic collapse due to coronary artery spasm was refractory to intravenously administered nitroglycerin but was relieved quickly with sublingually administered nifedipine. In certain selected patients in whom coronary artery spasm is responsible for myocardial collapse, the drug nifedipine may be effective in relieving this spasm and allowing for myocardial recovery.

• Authors: G S Kopf, A Riba, R Zito
• Journal: The Annals of thoracic surgery (Ann Thorac Surg) Vol. 34 Issue 4 Pg. 457-60 (Oct 1982) ISSN: 0003-4975 [Print] Netherlands
• PMID: 7138114 (Publication Type: Case Reports, Journal Article)

Chemical References

• Pyridines
• Nifedipine

Topics

• Coronary Vasospasm (complications, drug therapy)
• Heart Arrest (drug therapy, etiology)
• Heart Rate
• Hemodynamics
• Humans
• Hypotension (drug therapy, etiology)
• Intraoperative Complications
• Male
• Middle Aged
• Myocardial Revascularization
• Nifedipine (therapeutic use)
• Pyridines (therapeutic use)