HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

The relationships between the Ga-67 uptake and nuclear DNA Feulgen content in thyroid tumors: concise communication.

Abstract
It has been reported that Ga-67 uptake by malignant tumors differs somewhat according to the histologic type. Previously, we reported that uptake of Ga-67 is predictably low in well-differentiated adenocarcinoma of the thyroid gland but high in anaplastic carcinoma and malignant lymphoma. We studied the relationship between Ga-67 uptake and nuclear DNA content in four papillary adenocarcinomas, three follicular adenocarcinomas, three anaplastic carcinomas, and five malignant lymphomas of the thyroid gland. In anaplastic carcinoma and malignant lymphoma, the nuclear DNA content and proliferative index were significantly higher than in well-differentiated adenocarcinoma. These results suggest that there is close correlation between Ga-67 uptake and degree of malignancy of thyroid tumor cells.
AuthorsT Higashi, Y Watanabe, M Yamaguchi, T Hisada, T Mimura, K Ito, J R Allison
JournalJournal of nuclear medicine : official publication, Society of Nuclear Medicine (J Nucl Med) Vol. 23 Issue 11 Pg. 988-92 (Nov 1982) ISSN: 0161-5505 [Print] United States
PMID7131088 (Publication Type: Journal Article)
Chemical References
  • DNA, Neoplasm
  • Gallium Radioisotopes
Topics
  • Adenocarcinoma (analysis, diagnostic imaging)
  • Adenocarcinoma, Papillary (analysis, diagnostic imaging)
  • Carcinoma (analysis, diagnostic imaging)
  • DNA, Neoplasm (analysis)
  • Gallium Radioisotopes
  • Humans
  • Lymphoma (analysis, diagnostic imaging)
  • Radionuclide Imaging
  • Thyroid Neoplasms (analysis, diagnostic imaging)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: