A quantitative study of alpha-naphthyl acetate esterase-positive cells in non-Hodgkin's lymphomas and reactive lymph nodes.

Abstract

The numbers of alpha-naphthyl acetate esterase (ANAE)-containing cells (other than T lymphocytes) in non-Hodgkin's lymphomas (NHL) and reactive lymph nodes have been counted, using the Reichert-Jung (Kontron) MOP-AMO3 user-controlled image analyzer. Twenty specimens of NHL and ten reactive nodes were examined. Cells were demonstrated by their content of acid alpha-naphthyl acetate esterase (ANAE) in fixed frozen sections. It was found that lymphomas of high-grade malignancy contained much larger numbers of ANAE-positive cells (10.8-20.5%) than those of low-grade malignancy (1.4-4.1%). The number of ANAE-positive cells (1.4-3.2%) in reactive lymph nodes was similar to that in low-grade NHL nodes.

• Authors: J Crocker, E L Jones, R C Curran
• Journal: Journal of clinical pathology (J Clin Pathol) Vol. 35 Issue 10 Pg. 1066-8 (Oct 1982) ISSN: 0021-9746 [Print] England
• PMID: 7130417 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Naphthol AS D Esterase
• Carboxylic Ester Hydrolases

Topics

• Carboxylic Ester Hydrolases (metabolism)
• Cell Count
• Humans
• Lymph Nodes (enzymology, pathology)
• Lymphoma (enzymology, pathology)
• Naphthol AS D Esterase (metabolism)