Treatment of acute uncomplicated urinary tract infections by cephalexin, with special reference to the antibody-coated bacteria.

Abstract

In 68 college-age females with acute uncomplicated urinary tract infections (UTI), ACB testing revealed that 36.8% of the infections were localized in the kidney and 63.2% in the urinary bladder. Sixty-two patients who completed 10 days of therapy with cephalexin showed a clinical and bacteriologic cure on the last day of therapy. Ninety-seven percent of patients were free of UTI at 1 week post therapy. Cephalexin appeared to be equally effective in treatment of both ACB-positive and ACB-negative infections. Antibody-coated bacteria did not correlate with symptoms, response to therapy, or rate of recurrences.

• Authors: A Iravani, N Pryor, G A Richard
• Journal: International journal of clinical pharmacology, therapy, and toxicology (Int J Clin Pharmacol Ther Toxicol) Vol. 20 Issue 3 Pg. 97-100 (Mar 1982) ISSN: 0174-4879 [Print] Germany
• PMID: 7068290 (Publication Type: Journal Article)

Chemical References

• Cephalexin

Topics

• Adult
• Antibody-Coated Bacteria Test, Urinary
• Cephalexin (therapeutic use)
• Female
• Humans
• Recurrence
• Urinary Tract Infections (drug therapy, immunology, microbiology)