Abstract |
We studied plasma renin activity (PRA) in eight children before and after surgical correction of aortic coarctation. These eight children underwent a combination of low-sodium diet and diuresis before surgery, and PRA was measured shortly thereafter. Thirty-two to 51 months after successful surgical correction, PRA was measured again. The mean PRA was 21.4 +/- 1.3 ng/ml/hour (+/- SD) preoperatively and 5.5 +/- 1.5 ng/ml/hour postoperatively. These findings provide further evidence of the significance of increased renin- angiotensin activity in patients with aortic coarctation.
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Authors | F B Parker Jr, D H Streeten, B Farrell, M S Blackman, H M Sondheimer, G H Anderson Jr |
Journal | Circulation
(Circulation)
Vol. 66
Issue 3
Pg. 513-4
(Sep 1982)
ISSN: 0009-7322 [Print] United States |
PMID | 7046989
(Publication Type: Journal Article)
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Chemical References |
- Diuretics
- Angiotensin II
- Renin
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Topics |
- Adolescent
- Angiotensin II
(blood)
- Aortic Coarctation
(blood, complications, surgery)
- Child
- Child, Preschool
- Diet, Sodium-Restricted
- Diuretics
(therapeutic use)
- Humans
- Hypertension
(complications)
- Renin
(blood)
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