Sugar and dental caries: a review of human studies.

Abstract

Studies of special population groups, epidemiological surveys, controlled longitudinal studies of humans, and longitudinal studies on the effect of sugar substitutes indicate that frequent or high intake of sugary foods predisposes to dental decay. The relation is not always clear-cut, and most studies have important methodological problems and limitations. Longitudinal measurements of caries increments combined with multiple dietary histories are needed to clarity the association between caries and eating habits. The relative cariogenicity of specific foods can be assessed by a combination of in vitro tests, human in vivo tests, and experimental caries in animals. Human diets, however, vary in food items eaten and the frequency and sequence of eating, and these factors can affect the cariogenicity of a food. Therefore, reported correlations must be interpreted with caution.

• Authors: E Newbrun
• Journal: Science (New York, N.Y.) (Science) Vol. 217 Issue 4558 Pg. 418-23 (Jul 30 1982) ISSN: 0036-8075 [Print] United States
• PMID: 7046052 (Publication Type: Journal Article, Review)

Chemical References

• Cariogenic Agents
• Sweetening Agents
• Sucrose

Topics

• Adolescent
• Cariogenic Agents
• Child
• Child, Preschool
• Dental Caries (epidemiology, etiology)
• Diet, Cariogenic
• Feeding Behavior
• Food Preferences
• Humans
• Longitudinal Studies
• Sucrose (adverse effects, metabolism)
• Sweetening Agents (pharmacology)