Abstract |
A parasitological and immuno-hematological study was undertaken simultaneously in fifty South-East asian refugees at the time of their arrival in France. --in this series the frequency of individuals having a P2 erythrocyte phenotype is 80%. --54 % of these immigrants were found to be carriers of Clonorchis sinensis, a parasite rarely found in Europe. --in 40,7 % of these subjects infested by Clonorchis sinensis, the following properties were disclosed concerning the P1 allo-antibody: slow-P1 red cell agglutination at 22 degrees C, no hemolysis of P1 red cells in vitro, IgM antibody, in weak titers. The immuno-hematological study of the immuno-serums with respect to distomian antigens coupled with adsorption-elution using P1+++ red cells shows a close immunological relationship between the antibody of parasite origin and the anti-P1 allo-antibody.
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Authors | A Petit, T H Duong, J L Bremond, A Barrabes, C Binet, C Combescot, M E Leroux |
Journal | Revue francaise de transfusion et immuno-hematologie
(Rev Fr Transfus Immunohematol)
Vol. 24
Issue 2
Pg. 197-210
(Apr 1981)
ISSN: 0338-4535 [Print] France |
Vernacular Title | Allo-anticorps irréguliers anti-P1 et clonorchiase á Clonorchis sinensis. |
PMID | 7027412
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Anthelmintics
- Antibodies
- Blood Group Antigens
- Isoantibodies
- P Blood-Group System
- Mebendazole
- flubendazole
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Topics |
- Anthelmintics
(therapeutic use)
- Antibodies
(immunology)
- Blood Group Antigens
(immunology)
- Clonorchiasis
(blood, drug therapy)
- Clonorchis sinensis
(immunology)
- Humans
- Immunoelectrophoresis
- Isoantibodies
(immunology)
- Mebendazole
(analogs & derivatives, therapeutic use)
- P Blood-Group System
(genetics, immunology)
- Phenotype
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