[Irregular anti-P1 allo-antibodies and sinensis clonorchiasis].

Abstract

A parasitological and immuno-hematological study was undertaken simultaneously in fifty South-East asian refugees at the time of their arrival in France. --in this series the frequency of individuals having a P2 erythrocyte phenotype is 80%. --54 % of these immigrants were found to be carriers of Clonorchis sinensis, a parasite rarely found in Europe. --in 40,7 % of these subjects infested by Clonorchis sinensis, the following properties were disclosed concerning the P1 allo-antibody: slow-P1 red cell agglutination at 22 degrees C, no hemolysis of P1 red cells in vitro, IgM antibody, in weak titers. The immuno-hematological study of the immuno-serums with respect to distomian antigens coupled with adsorption-elution using P1+++ red cells shows a close immunological relationship between the antibody of parasite origin and the anti-P1 allo-antibody.

• Authors: A Petit, T H Duong, J L Bremond, A Barrabes, C Binet, C Combescot, M E Leroux
• Journal: Revue francaise de transfusion et immuno-hematologie (Rev Fr Transfus Immunohematol) Vol. 24 Issue 2 Pg. 197-210 (Apr 1981) ISSN: 0338-4535 [Print] France
• Vernacular Title: Allo-anticorps irréguliers anti-P1 et clonorchiase á Clonorchis sinensis.
• PMID: 7027412 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anthelmintics
• Antibodies
• Blood Group Antigens
• Isoantibodies
• P Blood-Group System
• Mebendazole
• flubendazole

Topics

• Anthelmintics (therapeutic use)
• Antibodies (immunology)
• Blood Group Antigens (immunology)
• Clonorchiasis (blood, drug therapy)
• Clonorchis sinensis (immunology)
• Humans
• Immunoelectrophoresis
• Isoantibodies (immunology)
• Mebendazole (analogs & derivatives, therapeutic use)
• P Blood-Group System (genetics, immunology)
• Phenotype