[Idiopathic orthostatic hypotension and the Shy-Drager syndrome: hemodynamic and pharmacological studies in seven patients (author's transl)].

Abstract

Idiopathic orthostatic hypotension (IOH) is a slowly progressive disease of the autonomic nervous system. The association of central lesions with those of IOH is characteristic of the Shy-Drager syndrome, which follows a rapidly unfavorable course, and can be distinguished from IOH, according to some authors, by anatomical and pharmacological features. Hemodynamic and pharmacological studies were conducted in 4 cases of IOH and 3 cases of the Shy-Drager syndrome in order to determine the localization and extent of the orthostatic regulatory disorder. No differences were found between the two groups and a common physiopathological mechanism for the two affections is suggested.

• Authors: P de Rohan-Chabot, G Said, J M Ziza
• Journal: Annales de medecine interne (Ann Med Interne (Paris)) Vol. 131 Issue 8 Pg. 483-8 ( 1980) ISSN: 0003-410X [Print] France
• Vernacular Title: Hypotension orthostatique idiopathique et syndrome de Shy-Drager. Etudes hémodynamiques et pharmacodynamiques chez sept sujets. Limites nosologiques.
• PMID: 7013598 (Publication Type: English Abstract, Journal Article)

Chemical References

• Renin

Topics

• Adult
• Aged
• Autonomic Nervous System Diseases (complications)
• Female
• Hemodynamics
• Humans
• Hypotension, Orthostatic (complications, diagnosis)
• Male
• Methods
• Middle Aged
• Renin (blood)
• Shy-Drager Syndrome (complications, diagnosis)
• Valsalva Maneuver