Ampicillin-resistant H influenzae cellulitis and shock in an adult.

Abstract

Over a three-day period, pharyngitis, neck swelling, deep voice, dysphagia, fever, and cellulitis of the anterior neck and upper chest developed in a 63-year-old woman. Sixteen hours following the institution of intravenous ampicillin, septic shock developed and the patient became comatose. Ampicillin-resistant Hemophilus influenzae type B was found in a culture taken from her blood and pharynx. In patients who have an upper respiratory tract infection and severe cellulitis of the neck, initial therapy should include chloramphenicol because of the possibility of ampicillin-resistant Hemophilus influenzae infection.

• Authors: J P Shea, J M Berman, G W McReynolds
• Journal: Otolaryngology and head and neck surgery (Otolaryngol Head Neck Surg (1979)) 1980 Nov-Dec Vol. 88 Issue 6 Pg. 681-3 United States
• PMID: 6970915 (Publication Type: Case Reports, Journal Article)

Chemical References

• Chloramphenicol
• Ampicillin

Topics

• Ampicillin (therapeutic use)
• Cellulitis (drug therapy, etiology)
• Chloramphenicol (therapeutic use)
• Female
• Haemophilus Infections (drug therapy)
• Haemophilus influenzae (drug effects)
• Humans
• Middle Aged
• Neck
• Penicillin Resistance
• Shock, Septic (etiology)