Yersinia arthritis in children.

Abstract

Over a 10-year period 37 children were hospitalized with infections of Yersinia enterocolitica III, IX or Yersinia pseudotuberculosis IA. The diagnosis was based on elevated antibody titres against these micro-organisms. Thirteen of the children had reactive arthritis caused by Yersinia. The duration of arthritis in the primary phase varied between 3 and 22 months, the average being 6.5 months. Two patients developed persistent arthritis. chemical synovectomy with osmic acid was performed in 3 children because of persistent synovitis in the knee joint. All 3 became asymptomatic after this therapy. The follow-up study of the patients with arthritis was performed after an average period of 4 years 7 months. The histocompatibility antigen HLA-B27 was found in 11 of the 13 children. This group included both patients with chronic arthritis and the 3 synovectomized children. Reactive arthritis in this material was a common, serious complication in an otherwise benign infection.

• Authors: R Leino, A L Mäkelä, A Tiilikainen, A Toivanen
• Journal: Scandinavian journal of rheumatology (Scand J Rheumatol) Vol. 9 Issue 4 Pg. 245-9 ( 1980) ISSN: 0300-9742 [Print] England
• PMID: 6969933 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• HLA Antigens
• HLA-B27 Antigen

Topics

• Adolescent
• Arthritis (drug therapy, etiology, immunology)
• Child
• Child, Preschool
• Feces (microbiology)
• Female
• Follow-Up Studies
• HLA Antigens
• HLA-B27 Antigen
• Humans
• Male
• Yersinia (immunology)
• Yersinia Infections (drug therapy, immunology)