Toxicity and efficacy of vitrectomy fluids: amphotericin B methyl ester in the treatment of experimental fungal endophthalmitis.

Abstract	The maximum nontoxic dose of amphotericin B methyl ester in vitrectomy infusion fluid was found to be 75 microgram/ml. Experimentally induced fungal endophthalmitis in rabbits was cured by vitrectomy using infusion fluid that contained 10 microgram/ml of amphotericin B methyl ester.
Authors	M Raichand, G A Peyman, C S West, G Hammond, K Zweig
Journal	Ophthalmic surgery (Ophthalmic Surg) Vol. 11 Issue 4 Pg. 246-8 (Apr 1980) ISSN: 0022-023X [Print] United States
PMID	6966778 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References	Gentamicins Amphotericin B
Topics	Amphotericin B (analogs & derivatives, therapeutic use, toxicity) Animals Candidiasis (drug therapy) Endophthalmitis (drug therapy) Gentamicins (therapeutic use) Infusions, Parenteral Rabbits Vitreous Body (surgery)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!