[Monoamine content of the blood in the experimental pharmacotherapy of alcoholic intoxication].

Abstract

Experiments on rabbits have shown that caffeine (10 mg/kg), ethimizol (10 mg/kg) and particularly bemegride (5 mg/kg) increase the blood adrenaline and noradrenaline content up to the level characteristic for intact animals under acute ethanol poisoning (2.5 g/kg per os). This effect has been found to be more remarkable on repeated administration. The shifts in the serotonin content are inconsistent in this case.

• Authors: K I Bender, L A Bobrova
• Journal: Farmakologiia i toksikologiia (Farmakol Toksikol) 1982 Nov-Dec Vol. 45 Issue 6 Pg. 71-5 ISSN: 0014-8318 [Print] Russia (Federation)
• Vernacular Title: Soderzhanie monoaminov v krovi pri éksperimental'noĭ farmakoterapii alkogol'noĭ intoksikatsii.
• PMID: 6891342 (Publication Type: English Abstract, Journal Article)

Chemical References

• Amines
• Blood Glucose
• Serotonin
• Caffeine
• Ethanol
• Bemegride
• Etimizol
• Norepinephrine
• Epinephrine

Topics

• Alcoholic Intoxication (blood, drug therapy)
• Amines (blood)
• Animals
• Bemegride (administration & dosage)
• Blood Glucose (analysis)
• Caffeine (administration & dosage)
• Epinephrine (blood)
• Ethanol (blood)
• Etimizol (administration & dosage)
• Humans
• Male
• Norepinephrine (blood)
• Rabbits
• Serotonin (blood)
• Time Factors