Pemphigus foliaceus and proteinuria induced by alpha-mercaptopropionylglycine.

Abstract

Pemphigus foliaceus and proteinuria occurred in a patient with cystinuria treated with alpha-mercaptopropionylglycine. This drug is similar to D-penicillamine in structure and function, and it is being used in patients who are unable to tolerate D-penicillamine. Although side effects of D-penicillamine are common, no major adverse reactions have been reported previously with alpha-mercaptopropionylglycine. Pemphigus foliaceus and proteinuria occurring during therapy with alpha-mercaptopropionylglycine and D-penicillamine are discussed.

• Authors: P A Lucky, F Skovby, S O Thier
• Journal: Journal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 8 Issue 5 Pg. 667-72 (May 1983) ISSN: 0190-9622 [Print] United States
• PMID: 6863624 (Publication Type: Case Reports, Journal Article)

Chemical References

• Amino Acids, Sulfur
• Tiopronin

Topics

• Amino Acids, Sulfur (adverse effects)
• Cystinuria (drug therapy)
• Humans
• Male
• Middle Aged
• Pemphigus (chemically induced, pathology)
• Proteinuria (chemically induced)
• Skin (pathology)
• Tiopronin (adverse effects, therapeutic use)