[Biogenic monoamines and their precursors in rats with spontaneous arterial hypertension].

Abstract

Content of tryptophane, tyrosine, serotonin, noradrenaline, adrenaline and dopamine was studied in blood serum and various brain regions of rats with genetically determined spontaneous form of hypertension. The arterial pressure of these animals was shown to depend on activity of noradrenaline-, serotonin- and dopaminergic systems of brain. Oppositely directed alterations in content of dopamine and noradrenaline were observed in various brain regions apparently as a result of changes in activity of the enzymes involved in the amines synthesis and degradation.

• Authors: P A Kaliman, N G Sergienko, N A Luchko, N N Brovina
• Journal: Voprosy meditsinskoi khimii (Vopr Med Khim) 1983 Mar-Apr Vol. 29 Issue 2 Pg. 69-73 ISSN: 0042-8809 [Print] Russia (Federation)
• Vernacular Title: Biogennye monoaminy i ikh predshestvenniki u krys so spontannoĭ arterial'noĭ gipertenzieĭ.
• PMID: 6858037 (Publication Type: English Abstract, Journal Article)

Chemical References

• Biogenic Amines
• Serotonin
• Tyrosine
• Tryptophan
• Dopamine
• Norepinephrine
• Epinephrine

Topics

• Animals
• Biogenic Amines (metabolism)
• Brain (metabolism)
• Dopamine (metabolism)
• Epinephrine (metabolism)
• Hypertension (genetics, metabolism)
• Norepinephrine (metabolism)
• Rats
• Serotonin (metabolism)
• Tryptophan (metabolism)
• Tyrosine (metabolism)