Hepatitis B virus: a possible cause of serositis in hemodialysis patients.

Abstract

An epidemiologic survey in a maintenance hemodialysis population of 300 patients was undertaken to relate the appearance of acute serositis (pericarditis, pleuritis or ascites) to HBsAg antigenemia. A significant number of incidents of serositis occurred in patients acutely or chronically infected with hepatitis B surface antigen (HBsAg) suggesting an etiologic role for the virus in the serositis of uremia. In 2 patients with both end-stage renal disease and chronic HBsAg antigenemia, immunofluorescent studies of serosal tissues showed fluorescent clusters interpreted to be HBs antigen-antibody complexes. It is concluded that an immunologic response to viremia may be one of the causes of serositis in uremia.

• Authors: M B Dave, Y J Choi, B D Cohen
• Journal: Nephron (Nephron) Vol. 33 Issue 3 Pg. 186-8 ( 1983) ISSN: 1660-8151 [Print] Switzerland
• PMID: 6843747 (Publication Type: Case Reports, Journal Article)

Chemical References

• Hepatitis B Surface Antigens

Topics

• Adult
• Female
• Hepatitis B Surface Antigens (analysis)
• Hepatitis B virus (immunology)
• Humans
• Kidney Failure, Chronic (complications, therapy)
• Male
• Pericarditis (etiology)
• Peritonitis (etiology)
• Pleurisy (etiology)
• Renal Dialysis (adverse effects)
• Retrospective Studies
• Serositis (etiology)