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A multivariable evoked potential measure applied to human epilepsy.

Abstract
Based upon a three-dimensional plot (response plane) representing a condensation of human sensory evoked potential data obtained from a paired stimulus protocol, a study was undertaken to investigate electrophysiological changes following sodium valproate administration in subjects with photosensitive epilepsy. Initial results in two patients and two normal subjects suggest that the measure is reproducible and sensitive to electrophysiological changes accompanying anticonvulsant administration.
AuthorsJ J Brickley, W W Sutherling, J A Messenheimer, S I Lee, R N Johnson
JournalNeuroscience letters (Neurosci Lett) Vol. 18 Issue 3 Pg. 353-60 (Jul 1980) ISSN: 0304-3940 [Print] Ireland
PMID6820485 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Valproic Acid
Topics
  • Adult
  • Brain (physiopathology)
  • Epilepsy (physiopathology)
  • Evoked Potentials (drug effects)
  • Humans
  • Male
  • Models, Neurological
  • Photic Stimulation
  • Valproic Acid (therapeutic use)

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