[Lysine acetylsalicylate in the control of postoperative pain in surgery of the upper abdomen].

Abstract

To evaluate the action of lysine acetylsalicylate in controlling post-operative pain a controlled double blind clinical trial was carried out in thirty patients subjected to surgical procedures on the upper gastrointestinal tract. The results or the trial support analgesic properties of the drug in the postoperative period and the absence of relevant untoward effects. The low toxicity and the absence of the side effects typical to narcotic analgesics suggest to study the analgesic effects of ASL with higher dosage schedules or different administrations in order to increase the analgesic potency of the drug in the post-operative period.

• Authors: A Andreoni, G B Cristofori, C Fochi, E Sganzerla
• Journal: Minerva anestesiologica (Minerva Anestesiol) Vol. 47 Issue 5 Pg. 221-8 (May 1981) ISSN: 0375-9393 [Print] Italy
• Vernacular Title: L'acetilsalicilato di lisina nel controllo del dolore post-operatorio nella chirurgia dell'addome alto.
• PMID: 6793922 (Publication Type: Clinical Trial, Comparative Study, Journal Article)

Chemical References

• Lysine
• Aspirin
• Pentazocine
• acetylsalicylic acid lysinate

Topics

• Abdomen (surgery)
• Adult
• Aspirin (analogs & derivatives, therapeutic use)
• Clinical Trials as Topic
• Female
• Humans
• Lysine (analogs & derivatives, therapeutic use)
• Male
• Middle Aged
• Pain, Postoperative (drug therapy)
• Pentazocine (therapeutic use)
• Random Allocation