Otitis media with effusion: results of treatment with a short course of oral prednisone or intranasal beclomethasone aerosol.

Abstract

A short course of prednisone suspension given in a decreasing dosage schedule for up to ten days was often effective (68%) in resolving mucoid otitis media with effusion (OME, middle ear effusion). No significant side effects were noted. Concommitant administration of sulfisoxazole suspension may have reduced the likelihood of activation of a quiescent infection of the middle ear. During the eight-month mean follow-up period, reaccumulation of the effusion was detected in 21% of the successfully treated children. Preliminary results of an unrelated, pilot project using intranasal beclomethasone dipropionate aerosol suggests that this novel method also may be efficacious in the treatment of OME.

• Authors: R H Schwartz
• Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery (Otolaryngol Head Neck Surg) 1981 May-Jun Vol. 89 Issue 3 Pt 1 Pg. 386-91 ISSN: 0194-5998 [Print] England
• PMID: 6791096 (Publication Type: Journal Article)

Chemical References

• Aerosols
• Beclomethasone
• Prednisone

Topics

• Administration, Oral
• Aerosols
• Beclomethasone (administration & dosage)
• Child
• Child, Preschool
• Follow-Up Studies
• Humans
• Infant
• Nose
• Otitis Media (drug therapy)
• Otitis Media with Effusion (drug therapy)
• Prednisone (administration & dosage)
• Recurrence
• Time Factors