ASdult Fanconi's syndrome with renal tubular acidosis in association with renal amyloidosis: occurrence in a patient with chronic lymphocytic leukemia.

Abstract

In a patient with chronic lymphocytic leukemia, multiple renal tubular defects developed in association with urinary excretion of K light chain proteins and peritubular deposits and casts of amyloid. Proximal tubular dysfunction, resembling adult Fanconi's syndrome, was suggested by an increased urinary loss of phosphate and urate and glycosuria. Renal tubular acidosis with hypokalemia and a marked impairment of the urinary concentrating mechanism were also observed.

• Authors: J Rochman, C Lichtig, D Osterweill, I Tatarsky, S Eidelman
• Journal: Archives of internal medicine (Arch Intern Med) Vol. 140 Issue 10 Pg. 1361-3 (Oct 1980) ISSN: 0003-9926 [Print] United States
• PMID: 6775610 (Publication Type: Case Reports, Journal Article)

Chemical References

• Immunoglobulin kappa-Chains

Topics

• Acidosis, Renal Tubular (complications, pathology)
• Amyloidosis (complications)
• Fanconi Syndrome (complications)
• Female
• Humans
• Hypokalemia (etiology)
• Immunoglobulin kappa-Chains
• Kidney Diseases (complications)
• Kidney Tubules (pathology)
• Leukemia, Lymphoid (complications)
• Middle Aged