Carprofen in osteoarthrosis.

Abstract

Two randomized double-blind trials with carprofen in osteoarthrosis were performed. The first compared carprofen with ibuprofen in 2 groups of 10 patients for 8 weeks and the second compared carprofen administered in two different schedules (100 mg in the morning plus 200 mg in the evening versus 100 mg 3 times daily) for 4 weeks, also in 2 groups of 10 cases. The trials indicate that carprofen is effective and well tolerated. In the first trial efficacy shows a small trend in favour of carprofen and in the second a slight superiority of the b.i.d. schedule as compared to t.i.d.

• Authors: B Klein
• Journal: European journal of rheumatology and inflammation (Eur J Rheumatol Inflamm) Vol. 5 Issue 4 Pg. 507-13 ( 1982) ISSN: 0140-1610 [Print] England
• PMID: 6759136 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Anti-Inflammatory Agents
• Carbazoles
• carprofen
• Ibuprofen

Topics

• Adult
• Anti-Inflammatory Agents (therapeutic use)
• Carbazoles (therapeutic use)
• Clinical Trials as Topic
• Double-Blind Method
• Drug Administration Schedule
• Female
• Humans
• Ibuprofen (therapeutic use)
• Male
• Middle Aged
• Osteoarthritis (drug therapy)
• Random Allocation