Effect of Escherichia coli endotoxin-mediated inflammation of one mammary quarter of the bovine udder on diapedesis into other quarters.

Abstract

Implantation of 1 microgram Escherichia coli endotoxin into one papillary duct of a bovine udder frequently resulted in a mild inflammatory process in the treated quarter which was measured by use of the Wisconsin mastitis test (WMT) on quarter fore milk samples. Inflammation of a fore quarter was usually (18/24) accompanied by a transient elevation in WMT score from the homolateral hind quarter, but rarely (1/25) from the contralateral quarter. Inflammation in a hind quarter rarely (2/26) affected the homolateral fore quarter and never (0/25) the contralateral quarter. The pattern of responses suggests tha absorption and initial removal of endotoxin from the mammary gland occurs via the lymphatic rather than the blood system.

• Authors: W D Schultze, A J Bramley
• Journal: The Journal of dairy research (J Dairy Res) Vol. 49 Issue 3 Pg. 381-5 (Aug 1982) ISSN: 0022-0299 [Print] England
• PMID: 6754782 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Endotoxins

Topics

• Animals
• Cattle
• Cell Movement
• Endotoxins (toxicity)
• Escherichia coli
• Female
• Leukocytes (physiology)
• Mammary Glands, Animal (physiopathology)
• Mastitis, Bovine (chemically induced, physiopathology)
• Milk (cytology)