Abstract |
L18-MDP(Ala), a synthetic derivative of muramyl dipeptide, enhanced resistance against Escherichia coli and Candida albicans infections in aged mice and younger adult mice whose defense mechanism(s) had been depressed by X-ray irradiation or by treatment with cyclophosphamide.
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Authors | Y Osada, M Mitsuyama, K Matsumoto, T Une, T Otani, H Ogawa, K Nomoto |
Journal | Infection and immunity
(Infect Immun)
Vol. 37
Issue 3
Pg. 1285-8
(Sep 1982)
ISSN: 0019-9567 [Print] United States |
PMID | 6752024
(Publication Type: Journal Article)
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Chemical References |
- Adjuvants, Immunologic
- Acetylmuramyl-Alanyl-Isoglutamine
- 6-O-stearoyl-N-acetylmuramyl-alanylisoglutamine
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Topics |
- Acetylmuramyl-Alanyl-Isoglutamine
(analogs & derivatives, pharmacology)
- Adjuvants, Immunologic
(pharmacology)
- Aging
- Animals
- Candidiasis
(immunology)
- Escherichia coli Infections
(immunology)
- Immunity, Innate
- Immunosuppression Therapy
- Male
- Mice
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