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Immunological analysis of women with repeated spontaneous abortions.

Abstract
The study deals with 9 women with recurrent abortions who do not possess the blocking factor which is present during normal pregnancy and which inhibits, nonspecifically, a cellular cytotoxicity reaction in vitro. Electrophoresis of the women's serum revealed an abnormal glycoprotein, migrating in the alpha-globulin zone, which gives a precipitate with an anti-gamma-globulin serum after mercaptoethanol treatment. These last two findings may indicate a possible abortion.
AuthorsJ Bousquet, D Fizet
JournalGynecologic and obstetric investigation (Gynecol Obstet Invest) Vol. 17 Issue 3 Pg. 113-9 ( 1984) ISSN: 0378-7346 [Print] Switzerland
PMID6706246 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • HLA Antigens
Topics
  • Abortion, Habitual (immunology)
  • Abortion, Spontaneous (immunology)
  • Chromatography, Gel
  • Cytotoxicity, Immunologic
  • Female
  • HLA Antigens (immunology)
  • Humans
  • Immunity, Cellular
  • Immunoelectrophoresis
  • Immunosuppression Therapy
  • Pregnancy

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