[Acute voluntary carpipramine poisoning with ventricular tachycardia].

A case of carpipramine overdose is reported. The patient was admitted with ventricular tachycardia 4 h after taking 2.40 g of the drug. This disappeared at the sixth hour. In overdoses with other tricyclics, ventricular tachycardia was successfully treated within 30 min of starting a sodium lactate perfusion. In the case presented, reversal of the ventricular tachycardia coincided with the half-life of the drug; the effects of perfusing 1000 ml sodium lactate over 2 h seemed doubtful. This sodium resistance may be related to a relative hypokalemia (3.4 mmol X 1(-1) ). The use of sodium lactate for the treatment of overdoses with drugs with short-half lives appeared questionable.
AuthorsJ P Racle, G Maman, C Beligon, D Curabet
JournalAnnales françaises d'anesthèsie et de rèanimation (Ann Fr Anesth Reanim) Vol. 3 Issue 1 Pg. 52-3 ( 1984) ISSN: 0750-7658 [Print] FRANCE
Vernacular TitleIntoxication volontaire aiguë par la carpipramine avec tachycardie ventriculaire.
PMID6703422 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Anti-Anxiety Agents
  • Dibenzazepines
  • Benzodiazepines
  • carpipramine
  • Acute Disease
  • Adult
  • Anti-Anxiety Agents
  • Benzodiazepines
  • Dibenzazepines (poisoning)
  • Electrocardiography
  • Female
  • Heart Ventricles
  • Humans
  • Tachycardia (chemically induced)

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