Vitamin E, catalase, manganous or cobaltous ions and dithiothreitol protect against Tween 20-induced hemolysis of vitamin E-deficient chick and kid erythrocytes.

Abstract

The effective Tween 20 concentration at which 70% hemolysis was achieved in vitro correlated with the plasma vitamin E content of chicks (r = 0.85). Addition of catalase, MnCl2, CoCl2 or dithiothreitol in vitro showed significant protection against the hemolysis induced by Tween 20 in vitamin E-deficient chick and kid erythrocytes.

• Authors: T Hamada, K Hodate, E Nakayama
• Journal: Experientia (Experientia) Vol. 40 Issue 3 Pg. 258-9 (Mar 15 1984) ISSN: 0014-4754 [Print] Switzerland
• PMID: 6698183 (Publication Type: Journal Article)

Chemical References

• Polysorbates
• Vitamin E
• Cobalt
• Manganese
• Catalase
• Dithiothreitol

Topics

• Animals
• Catalase (metabolism)
• Chickens
• Cobalt (pharmacology)
• Dithiothreitol (pharmacology)
• Goats
• Hemolysis (drug effects)
• Male
• Manganese (pharmacology)
• Polysorbates (pharmacology)
• Vitamin E (pharmacology)
• Vitamin E Deficiency (blood)