HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Lobular carcinoma of the breast metastatic to bone with unusual clinical, radiologic, and pathologic features mimicking osteopoikilosis.

Abstract
A 55-year-old woman who underwent a right radical mastectomy for infiltrating lobular carcinoma was found to have multiple diffuse osteoblastic bone lesions. Since she was asymptomatic, had no elevation of alkaline phosphatase, and the lesions did not take up technetium pyrophosphate on bone scan, she was thought to have osteopoikilosis. An iliac bone biopsy was performed that showed greatly thickened bony trabeculae with diffuse delicate marrow fibrosis entrapping easily overlooked short strands of small malignant cells. The histologic picture also closely resembled osteopoikilosis. Although infiltrating lobular carcinoma has been recognized as separate from ductal carcinoma in the primary site, its recognition in metastatic foci is still vague. Attention is drawn to its histologic appearance in skeletal metastases so that such lesions will be more recognizable in the future.
AuthorsL Ghandur-Mnaymneh, L E Broder, W A Mnaymneh
JournalCancer (Cancer) Vol. 53 Issue 8 Pg. 1801-3 (Apr 15 1984) ISSN: 0008-543X [Print] United States
PMID6697319 (Publication Type: Case Reports, Comparative Study, Journal Article)
Topics
  • Bone Neoplasms (diagnostic imaging, pathology, secondary)
  • Breast Neoplasms (diagnostic imaging)
  • Carcinoma (diagnostic imaging)
  • Diagnosis, Differential
  • Female
  • Humans
  • Ileum (pathology)
  • Middle Aged
  • Osteopoikilosis (diagnostic imaging)
  • Osteosclerosis (diagnostic imaging)
  • Radiography

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: