Levels of vitamin D-metabolites in a case of acro-osteolysis syndrome.

Abstract

On the initial examinations of a 17-year-old boy with acro-osteolysis syndrome, the levels of serum 25-hydroxycholecalciferol (25OHD) were low, whereas serum levels of 1,25-dihydroxycholecalciferol (1,25(OH)2D) were normal. Administration of 1 alpha-hydroxycholecalciferol (1OHD) failed to improve the osteoporosis, although the serum 25OHD level rose to normal. It is unlikely that impaired bone remodeling due to abnormal vitamin D-metabolism was a primary defect in our patient.

• Authors: T Sakano, S Hyodo, Y Nishi, M Kobayashi, T Tanaka, K Yamaoka, Y Seino, T Usui
• Journal: Acta paediatrica Scandinavica (Acta Paediatr Scand) Vol. 72 Issue 4 Pg. 617-20 (Jul 1983) ISSN: 0001-656X [Print] Sweden
• PMID: 6688697 (Publication Type: Case Reports, Journal Article)

Chemical References

• Hydroxycholecalciferols
• Calcitriol
• Calcifediol
• alfacalcidol

Topics

• Adolescent
• Bone Resorption (blood)
• Calcifediol (blood)
• Calcitriol (blood)
• Foot (diagnostic imaging)
• Hand (diagnostic imaging)
• Humans
• Hydroxycholecalciferols (therapeutic use)
• Male
• Osteolysis (blood)
• Osteoporosis (blood)
• Radiography
• Syndrome